Wednesday 22nd of September 2021

on their way to wuhan from nonprofit US-based ecohealth alliance...


Humanized mouse is a general term that refers to a mouse that has been engrafted with something from a human. This could be a short strand of human DNA, human tissue, a human tumor, a humanized immune system, or parts of the human microbiome.




Scientists working under a 2014 NIH grant to the EcoHealth Alliance to study bat coronaviruses combined the genetic material from a “parent” coronavirus known as WIV1 with other viruses. They twice submitted summaries of their work that showed that, when in the lungs of genetically engineered mice, three altered bat coronaviruses at times reproduced far more quickly than the original virus on which they were based. The altered viruses were also somewhat more pathogenic, with one causing the mice to lose significant weight. The researchers reported, “These results demonstrate varying pathogenicity of SARSr-CoVs with different spike proteins in humanized mice.”


But the terms of the grant clearly stipulated that the funding could not be used for gain-of-function experiments. The grant conditions also required the researchers to immediately report potentially dangerous results and stop their experiments pending further NIH review. According to both the EcoHealth Alliance and NIH, the results were reported to the agency, but NIH determined that rules designed to restrict gain-of-function research did not apply.

The Intercept consulted 11 scientists who are virologists or work in adjacent fields and hold a range of views on both the ethics of gain-of-function research and the Covid-19 origins search. Seven said that the work appears to meet NIH’s criteria for gain-of-function research.

One said that the experiment “absolutely does not meet the bar” for gain-of-function research. “You can’t predict that these viruses would be more pathogenic, or even pathogenic at all in people,” said Angela Rasmussen, a virologist with the Vaccine and Infectious Disease Organization at the University of Saskatchewan. “They also did not study transmissibility at all in these experiments,” meaning that the scientists did not look at whether the viruses could spread across a population.

Three experts said that, while they did not have enough knowledge of U.S. policies to comment on whether the research met NIH criteria, the experiment involving humanized mice was unnecessarily risky.

One virologist, Vincent Racaniello, a professor of microbiology and immunology at Columbia University, said while he considered the mouse experiment described in the document to clearly fall into the gain-of-function category, he didn’t see it as problematic. “You can do some kinds of gain-of-function research that then has unforeseen consequences and may be a problem, but that’s not the case here,” said Racaniello.

Robert Kessler, communications manager for EcoHealth Alliance, denied that the work on the humanized mice met the definition of gain-of-function research. Kessler insisted that bat viruses are not potential pandemic pathogens because, he said, “a bat virus is not known to be able to infect humans.” The proposal justified the work on WIV1 by explaining that it is “not a select agent” — referring to a list of closely monitored toxins and biological agents that have the potential to pose a severe threat to public health — and “has not been shown to cause human infections, and has not been shown to be transmissible between humans.”


Read more:


Why would a small mouse try to escape from a lab? Brains: "To take over the world, Pinky..."


See also:










In a maniacal move of wild desperation – or as an excuse to try out the most extreme powers of his office – he is using every weapon that he believes he has to assure compliance with his dream of injecting as many arms as possible. Only then will we crush the virus, all thanks to his leadership, all the complaints about “freedom” be damned – and never mind that the realization of his dream did not work in Israel or the UK. 

What are the immediate problems here? At least five:


1. The Biden mandate pretends that the only immunity is injected, not natural. And so it has been from the beginning of this pandemic, even though all science for at least a year – actually you can say centuries – contradicts that. Indeed, we’ve known about natural immunity since 400 B.C when Thucydides first wrote of the great Athens plague that revealed that “they knew the course of the disease and were themselves free from apprehension.” Biden’s mandate could affect 80 million people but far more than that have likely been exposed and gained robust immunity regardless of vaccination status. 


We Gustaphians need to comment: On average, vaccination has protected more people than no vaccination. One could argue that protecting the weak and the non-disease resistant individuals tends to weaken the species. It's an iffy argument but plausible, but we have no parallel placebo test to verify this hypothesis. Because we are a relatively compassionate species, we help the weak and the useless survive. Some people need to be vaccinated, some don't, but we have no idea as who's who until they get sick and die: Small pox, anthrax, polio, measles of various kinds, ebola, flu (which kill a lot of unvaccinated people every year) and the Sweating disease then... So, do we play the odds and even game, and who's going to foot the bill for hospitalisation of unvaxxed people? Who is going to pay for the vaccines? 



2. This natural immunity is long-lasting and broad, and we’ve known that since last year when the first studies revealed it. You can say that the addition of a vaccine provides even more but it’s new and untested relative to most drugs approved by regulators, and many people are concerned about possible side effects of this vaccine that was approved much faster than any drug in my lifetime – and there is not one living human being in a position to say with certainty that these skeptics are wrong. 


Our natural immunity is limited. During the plagues, a lot of people died. Their natural immunity was not the best or they really got infected badly. Either way, the human species as a whole (as mentioned many times by Gus on this site) is a relatively weak unfinished natural work in progress. We are lucky we survived, by stealth and deceit, by stealing and by scientific improvements, including vaccination and by cesarian birth



3. The mandate presumes that everyone is equally susceptible to severe outcomes from getting exposed to the virus, which we’ve known is not true since at least February 2020. In this entire 18-month fiasco, we’ve not seen any serious high-level communication about the huge range of demographic gradients in infection based on both age and overall health. This ignorance is a consequence of poor public-health messaging, and is grossly irresponsible. The aggregated mandate from the Biden administration ignores this completely, as did the models that suggested lockdowns in the event of a virus from the Spring of 2020


Here, the odds are not that everyone is equally susceptible to severe outcomes from getting exposed to the virus. We know this. But what we don't know is who is not susceptible to severe outcomes from getting exposed to the virus and who is. On relative bet, we know that the rate of infection is such and such and the rate of deaths is thus... On the law of probability, anyone above 80 has close to zero chance of surviving the disease that can be transmitted by "healthy" younger people easily.



4. Biden seems still of the belief that vaccines stop infection (he claimed this many times) and spread but we know with certainty that this is not the case, and even the CDC admits it. The best guess at this point is that it can help in preventing hospitalization and death but this experiment is still in its early stages, and the relationship between cause and effect in human affairs is not as easy as throwing around two data sets and saying one caused the other. Most cases in the developed world now are occurring among the vaccinated – and we all know this because we have vaccinated friends who got Covid anyway. Some have died. We are not idiots, contrary to what the Biden administration believes. Nor do any of us have all the knowledge and answers. And it is precisely because science is uncertain that the decisions surrounding it need to be decentralized, depoliticized, and open to correction rather than being imposed by top-down mandates. 



Vaccines do not stop the spread of infection but prevent people from getting sick from infection. At this stage, the vaccinated people may prove to be more of a danger to unvaccinated people than the reverse, because vaccinated people may not know they carry the disease and could spread it to non-vaccinated people. THIS IS THE CRUX OF THE ARGUMENT FOR GETTING MORE PEOPLE VACCINATED than not.



5. Biden’s order flies in the face of basic human freedoms and rights. There is no other way to put it. And it is this fact that is the most prescient for the multitudes who are right now seething in anger that one man who happens to hold power can make health decisions for the whole population regardless of their perfectly rational judgements. When the needle filled with liquid is forced into the arms of people who either have natural immunities or do not fear exposure to the pathogen, it gets personal, and people get really mad, especially after they are still forced into masks and denied other essential rights


Imagine you lived before the end of the 19th century. Your rights and freedoms would have been bullshit on toasts. Rights and Freedoms have been illusions of RECENT democracy, until it suits the system to reduce your rights and freedoms, in the national interest... Biden is the dude WHO WROTE THE "PATRIOT ACT". Think about it. He is an expert at removing your whatever. But this is not new. All he did was codify the existing limits. The main problem is that you do not know your natural immunity until tested by infection and 90 per cent of hospitalisation are due to people who thought they had natural immunity... For older people, us who have seen blue murder and wars, we have to play the odds of the game and get the jab (hoping it will work!!!!!!)... The rest is politicking of no consequence for our limited future..