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Antibiotic-resistant “superbugs” – which the World Health Organization calls one of the top global threats to public health – usually conjure images of hospital settings. But research may point to a less-obvious source: the family dog.

Researchers warned of “an international public health risk” after finding antibiotic-resistant bacteria in a range of different types of raw dog food.

 

“The trend for feeding dogs raw food may be fuelling the spread of antibiotic resistant-bacteria”, the researchers said in a press release for their study, to be presented at the European Congress of Clinical Microbiology & Infectious Diseases.

Separate research to be presented at the same conference found resistance to a last-resort antibiotic may be passing between pet dogs and their owners.

Antibiotic resistant bugs can render minor injuries and common infections potentially deadly.

Resistance has grown in recent years because of the overuse of such drugs in humans and farm animals.

In the dog food study, a team from the University of Porto analysed 55 samples of dog food from 25 brands – including 14 raw frozen types – looking for Enterococci bacteria.

The bacteria can live harmlessly in human and animal intestines but can be dangerous in other parts of the body and can be resistant to antibiotics.

Researchers found that all of the raw dog food samples contained antibiotic-resistant Enterococci, including bacteria resistant to the last-resort antibiotic linezolid.

 

Genetic sequencing revealed that some of these antibiotic-resistant bacteria in the raw dog food were the same kind found in hospital patients in the UK, Germany and the Netherlands.

“The close contact of humans with dogs and the commercialisation of the studied brands in different countries poses an international public health risk,” said researcher Ana Freitas.

“European authorities must raise awareness about the potential health risks when feeding raw diets to pets and the manufacture of dog food, including ingredient selection and hygiene practices, must be reviewed.”

 

She added that dog owners should wash their hands after handling pet food and disposing of faeces.

In a separate study, which has not yet been submitted to a medical journal for publication, another team from Portugal tested pet owners and animals from 80 households for bacteria with the MCR-1 gene, which provides resistance to the last-resort antibiotic colistin.

All 126 humans were healthy, while half of the 102 pets sampled had either skin or urinary tract infections.

Four humans and eight dogs tested positive for bacteria carrying MCR-1, and in two households the gene was found in both the dog and its owner.

“Genetic analysis of the samples suggested that in one of these two cases, the gene had been transmitted between pet and owner,” he research said, adding that it was thought the gene passed from dog to human.

 

Read more:

https://www.theguardian.com/society/2021/jul/10/raw-dog-food-may-be-fuelling-spread-of-antibiotic-resistant-bacteria

don't despair...

Scientists have found a new way to kill antibiotic-resistant bacteria. The new approach disarms their natural defense mechanism, making existing antibiotics more lethal.

 

The study, conducted in lab dishes and mice, offers a promising strategy for taking down so-called superbugs without needing to make brand-new antibiotics. 

"You want to make the already existing antibiotics with good safety profiles more potent," and with the help of a few newfound chemicals, the research team did just that, said senior author Evgeny Nudler, a professor of biochemistry at the New York University Grossman School of Medicine and an investigator with the Howard Hughes Medical Institute. 

In the new study, published Thursday (June 10) in the journal Science, the team took aim at Staphylococcus aureus and Pseudomonas aeruginosa, two bacteria that show pervasive resistance to multiple drugs and rank among the leading causes of hospital-acquired infections. These bacteria rely on an enzyme called cystathionine gamma-lyase (CSE) to counter the toxic effects of bactericidal antibiotics, drugs that kill bacteria rather than just slowing their growth. 

 

Read more:

https://www.livescience.com/game-changer-antibiotic-resistant-superbugs.html

 

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dead meat...

 

A single property in the Northern Territory has been identified as the source of toxic horse meat, believed responsible for a spate of dog deaths in Victoria.

Key points:
  • Authorities have traced toxic horse meat back to a single property in Central Australia
  • At least 23 pet dogs have died, and 67 have been hospitalised in Victoria from indospicine poisoning
  • Australia exported more than 800 tonnes of "edible horse" meat in 2020

Authorities are not naming the location but have visited the property and interviewed its manager — who is said to be shocked by what has happened.

It is understood the property sold a truckload of about 25 horses, but they were not intended to go to Victoria.

"I have been on the property and discussed the situation with the manager and he was completely unaware that the [final] destination of the horses was Victoria for manufactured pet food," Peter Saville, the NT's principal veterinary officer, said.

"The manager's understanding was the horses would go to a meatworks in Queensland for human consumption and our investigation has suggested the horses were re-directed [to Victoria] due to COVID lockdowns."

Dr Saville said samples had been collected from another 80 horses on the property, which will be tested for levels of the toxin indospicine.

When asked if the toxic horse meat would have been harmful to humans, Dr Saville said "not necessarily".

"Humans are far more tolerant to low-levels of indospicine than dogs and the amount of meat in a human diet is much lower than a dog diet ... given dogs are repeatedly fed the same diet almost every day."

 

Read more:

https://www.abc.net.au/news/rural/2021-08-10/contaminated-pet-food-linked-to-horses-from-nt-property/100364254

 

Reaf from top.

 

 

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